Mnemosyne : Mnemonic synergy
ALEXANDRE Frédéric (researcher) FIRMO DRUMOND Thalita (PhD student) GARENNE André (MCU) HINAUT Xavier (researcher) KAUSHIK Pramod (PhD student) NALLAPU Bhargav (PhD student) PADIOLLEAU Guillaume (PhD student) PAGLIARINI Silvia (PhD researcher) ROUGIER Nicolas (researcher) SANKAR Remya (PhD student) STROCK Anthony (PhD researcher) VIEVILLE Thierry (researcher)
For any further information, please contact Dr Frédéric ALEXANDRE.
Mnemosyne is a team in computer science embedded in a biological and clinical environment. We design models of the brain circuitry and of its pathologies. We aim to better explore strategies of the cerebral architecture to learn and represent different kinds of information. We insist on the effectiveness of our models, including performances, reproducibility and application to realistic tasks.
We work on four thematics :
- Integrative and cognitive neuroscience
The aim is to build, on an overwhelming quantity of data, a simplifying and interpretative grid suggesting homogenous local computations and a structured and logical plan for the development of cognitive functions.
- Computational neuroscience
It consists in exploring more technically and theoretically the relations between structures and functions in the brain using methods from computer science and applied mathematics.
- Machine learning
Our objective is to propose on-line learning systems, where several modes of learning have to collaborate and where the protocols of training are realistic.
- Autonomous robotics
Our goal is to make autonomy possible, by various means corresponding to endow robots with an artificial physiology, to give instructions in a natural and incremental way and to prioritize the synergy between reactive and robust schemes over complex planning structures.
Our research work is at the frontier between integrative and computational neuroscience. We propose to model the brain as a system of active memories in synergy and in interaction with the internal and external work.
On the basis of current knowledge and experimental data, we develop models of the main cerebral structures, taking a specific care of the kind of mnemonic function they implement and of their interface with other cerebral and external structures. Then, in a systemic approach, we build the main behavioral loops involving cerebral structures connecting a wide spectrum of actions to various kinds of sensations. We observe at the behavioral level the properties emerging from the interaction between these loops.
Our original approach is particularly fruitful for investigating cerebral structures which are difficult to comprehend because of the rich and multimodal information flows they integrate. It also permits to revisit and enrich algorithms and methodologies in machine learning and in autonomous robotics. In addition, it enables to elaborate hypotheses to be tested in neuroscience and medicine, while offering to these latter domains a new ground of experimentation similar to their daily experimental studies.
- Refinement of the models of pavlovian and reinforcement conditioning, taking a better account of the nature (input and output) and of the modulation of information.
- Design of software libraries that allow checking characteristics needed to switch from experimental models to effective models and promotion of good practice in model design.
- Uniting mechanisms of information acquisition and representation in a single architecture performing a single task.
- Design of a platform to generate virtual environments
Criteria : Author : "Frederic,Alexandre", Publication type : "('ART')"
Number of occurrences founded : 49.
- [Re] The Wisconsin Card Sorting Test: Theoretical analysis and modeling in a neuronal network
- Pauline Bock, Frédéric Alexandre
- The ReScience journal, GitHub, 2019, 3 (1), pp.5
- Bio-inspired analysis of deep learning on not-so-big data using data-prototypes
- Thalita Drumond, Thierry Viéville, Frédéric Alexandre
- Frontiers in Computational Neuroscience, Frontiers, 2019, 12, ⟨10.3389/fncom.2018.00100⟩
- Pattern Separation in the Hippocampus: Distinct Circuits under Different Conditions
- Randa Kassab, Frédéric Alexandre
- Brain Structure and Function, Springer Verlag, 2018, 223 (6), pp.2785-2808. ⟨10.1007/s00429-018-1659-4⟩
- Changements socio-environnementaux et dynamiques rurales en Afrique de l’Ouest
- Catherine Mering, Frédéric Alexandre
- Espace Geographique, Éditions Belin, 2018, 47 (3), pp.193. ⟨10.3917/eg.473.0193⟩
- Sustainable computational science: the ReScience initiative
- Nicolas Rougier, Konrad Hinsen, Frédéric Alexandre, Thomas Arildsen, Lorena Barba, Fabien C. Y. Benureau, C. Titus Brown, Pierre de Buyl, Ozan Caglayan, Andrew P. Davison, Marc André Delsuc, Georgios Detorakis, Alexandra K. Diem, Damien Drix, Pierre Enel, Benoît Girard, Olivia Guest, Matt G. Hall, Rafael Neto Henriques, Xavier Hinaut, Kamil S Jaron, Mehdi Khamassi, Almar Klein, Tiina Manninen, Pietro Marchesi, Dan Mcglinn, Christoph Metzner, Owen L. Petchey, Hans Ekkehard Plesser, Timothée Poisot, Karthik Ram, Yoav Ram, Etienne Roesch, Cyrille Rossant, Vahid Rostami, Aaron Shifman, Joseph Stachelek, Marcel Stimberg, Frank Stollmeier, Federico Vaggi, Guillaume Viejo, Julien Vitay, Anya Vostinar, Roman Yurchak, Tiziano Zito
- PeerJ Computer Science, PeerJ, 2017, 3, pp.e142. ⟨10.7717/peerj-cs.142⟩